What is CBG?

What is CBG?

Cannabigerol (CBG) is a compound present in the cannabis plant that has recently generated interest for its potential therapeutic properties. Like other cannabinoids such as CBD, CBG does not produce psychoactive effects, meaning it does not create the “high” feeling associated with marijuana use. Although found in smaller quantities than other cannabinoids, CBG is a promising compound in scientific research.

How long has CBG been around?

CBG was first isolated in 1964 by Israeli researchers, but it was not until the 1980s that its therapeutic potential began to be investigated. For many years, CBG was considered a secondary cannabinoid due to its low concentration in the cannabis plant. However, in the last decade, interest in CBG has increased significantly, and numerous studies are currently being conducted to explore its potential therapeutic uses.

What therapeutic potential does CBG have?

The therapeutic properties of CBG are currently being studied, due to its safety profile and lack of psychoactive effects. Researchers have found preliminary evidence that CBG could be useful in treating various health conditions, such as pain, inflammation, Huntington's disease, cancer, and antibiotic-resistant bacterial infections.

While there is no FDA-approved CBG-based medication yet, research in this area is promising.

Cannabigerol (CBG) has been the subject of several investigations, such as the following studies stored in the United States National Library of Medicine:

• " Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats" published in the European Journal of Pharmacology. This article explores the preclinical evidence supporting the use of CBG to stimulate appetite. You can find it at: https://www.ncbi.nlm.nih.gov/pubmed/25914732

• " Neuroprotective properties of cannabigerol in Huntington's disease: studies in R6/2 mice and 3-nitropropionate -lesioned mice" published in Neurotherapeutics. This article discusses preclinical evidence suggesting that CBG may be useful in the treatment of Huntington's disease. You can find it at: https://www.ncbi.nlm.nih.gov/pubmed/25269802

• "Antibacterial Cannabinoids from Cannabis sativa : A Structure-Activity Study " published in the Journal of Natural Products. This article investigates the antibacterial activity of CBG and other cannabinoids. You can find it at: https://pubs.acs.org/doi/abs/10.1021/np5009007

How is this made?

Like CBD, CBG is extracted from the Cannabis sativa plant, but strains with high levels of CBG are required for effective production. The extraction processes for CBG are similar to those for CBD and include:

1. CO2 extraction: This method uses supercritical carbon dioxide to extract CBG from the cannabis plant, resulting in a safe and pure end product.

2. Solvent extraction: This method uses solvents such as ethanol, butane or propane to extract the CBG from the plant. It is important to ensure that no solvent residue remains in the final product.

3. Oil extraction: Olive oil or coconut oil can be used to extract CBG from the cannabis plant. These methods are less efficient than others, but are popular options for home production.

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